One often thinks that things always change especially in an area of technology. But many things also are constant. Much goes with you even to the next job. However, what goes with you are frequently not so much the technical skills or accomplishments.
What drives one forward in a career? And the surprisingly important issue: What will increase your paycheck? How does one negotiate the best job conditions?
How do you handle the various forces that pull you in various directions if you are a contributing member of a open source project. How do you enter a project and what are the signs that time with a project may be coming to an end. There is a life cycle to this one as well.
And finally there is the issue of burn out (and to put it plainly: Boredom). Experiences and observations how others have dealt with it.